Kris and Bruce Jenner have separated after 22 years of marriage.
The former couple—who have two daughters, Kendall, 17, and Kyle, 16, together and four children each from previous relationships—have confirmed they have amicably decided to end their relationship.
The Keeping Up with the Kardashians stars told E! News: "We are living separately and we are much happier this way.
"But we will always have much love and respect for each other.
"Even though we are separated, we will always remain best friends and, as always, our family will remain our number one priority."
Kris, 57, previously brushed off rumors they had split after Bruce moved out of their family home in Calabasas, California, and into his own beach house in Malibu.
She said: "We just laugh it off. We love each other and just laugh about it...
"These kind of stories have been circulating for the last couple of years."
Their split comes shortly after they argued about owning a gun and whether their teenage daughters should drop out of school.
Olympic medallist Bruce, 63—who was also previously married to Linda Thompson, with whom he has two sons, Brandon and Brody, and also to his first wife Chrystie Crownover, with whom he has a son Burt and daughter Casey—recently revealed he is battling skin cancer after undergoing a procedure on his nose.
Kris, whose self-titled talk show was cancelled after one season, has four children, Kourtney, Kim, Khloe, and Rob Kardashian with her late ex-husband Robert Kardashian.